Pharmacological Effects of Elenoside, an Arylnaphthalene Lignan.
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چکیده
منابع مشابه
Potent Cytotoxic Arylnaphthalene Lignan Lactones from Phyllanthus poilanei
Two new (1 and 2) and four known arylnaphthalene lignan lactones (3-6) were isolated from different plant parts of Phyllanthus poilanei collected in Vietnam, with two further known analogues (7 and 8) being prepared from phyllanthusmin C (4). The structures of the new compounds were determined by interpretation of their spectroscopic data and by chemical methods, and the structure of phyllanthu...
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This paper deals with the effects of elenoside, (3-hidroxymethyl-1-methoxy-5,6-methylene-dioxy-4-(3,4-methylenedioxyphenyl)-2-naftoic acid lactone-beta-D-glucoside) an arylnaphthalene lignan with broad spectrum cytotoxicity in a human tumor cell line panel, isolated from Justicia hyssopifolia (Acanthaceae) grown in the Canary Islands (Spain), on isolated cardiac auricle of rabbits, urinary excr...
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Arylnaphthalene lignan lactones are naturally occurrmg dimers in Plants and known to have potential use in medicine 1,2. A few of them are reported to be highly to&; others find use as antioxidants and insecticides3. Cleistanthus col1inu.y (Roxb.) Benth. & Hookf. (family: Euphorbiaceae) is a highly poisonous plant. All parts of it are reported to be toxic and employed as a suicidal, homicidal, ...
متن کاملPatavine, a new arylnaphthalene lignan glycoside from shoot cultures of Haplophyllum patavinum.
A new arylnaphthalene lignan glycoside, patavine (1), together with five known lignans, justicidin B (2), diphyllin (3), tuberculatin (4), majidine (5), and arabelline (6) were isolated from shoot cultures of Haplophyllum patavinum. The structure of the new compound was elucidated by extensive one-dimensional (1D) and two-dimensional (2D) NMR experiments and mass spectrometry. The cytotoxicity ...
متن کاملToxicity and Neuropharmacological Effects of Elenine
Elenine is the aglycone of elenoside, a cytotoxic arylnaphthalene lignan (NSC 644013-W/1) derived from Justicia hyssopifolia. (Family: Acanthaceae). Elenoside is a β-D-glucoside, with a similar chemical structure to etoposide, exhibiting central depressant activity. In the present study, elenine was given to mice and rats at doses of 10, 20, and 40 mg/kg. Acute toxicity (24 h) and general behav...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2001
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.24.254